| Publication | View |
| Daniel Z. Bar, Ester Neufeld, Naomi Feinstein, and Yosef Gruenbaum
Gliotoxin Reverses Age-Dependent Nuclear
Morphology Phenotypes, Ameliorates Motility,
but Fails to Affect Lifespan of Adult
Caenorhabditis elegans (2009) | View this publication |
| Miron Prokocimer, Maya Davidovich, Malka Nissim-Rafinia, Naama Wiesel-Motiuk, Daniel Z. Bar, Rachel Barkan, Eran Meshorer, Yosef Gruenbaum
Nuclear lamins: key regulators of nuclear structure and activities (2009) | View this publication |
| Kfir Sharabi, Anat Hurwitz, Amos J. Simon, Greg J. Beitel, Richard I. Morimoto, Gideon Rechavi, Jacob I. Sznajder, and Yosef Gruenbaum,
Elevated CO2 levels affect development, motility, and fertility and extend life
span in Caenorhabditis elegans (2009) | View this publication |
| Yosef Gruenbaum
The curious case of The ageing cells (2009) | View this publication |
| Eran Meshorer and Yosef Gruenbaum
NURd keeps chromatin young (2009) | View this publication |
| Naama Wiesel, Anna Mattout, Shai Melcer, Naomi Melamed-Book, Harald Herrmann, Ohad Medalia, Ueli Aebi, Yosef Gruenbaum
Laminopathic mutations interfere with the assembly,
localization, and dynamics of nuclear lamins (2008) | View this publication |
| Eran Meshorer and Yosef Gruenbaum
Gone with the Wnt/Notch: stem cells laminopathies, progeria, and aging (2008) | View this publication |
| Eran Meshorer & Yosef Gruenbaum
Rejuvenating premature aging (2008) | View this publication |
| Cohen M, Santarella R, Wiesel N, Mattaj I, Gruenbaum Y.
Electron microscopy of lamin and the nuclear lamina in Caenorhabditis elegans. (2008) | View this publication |
| Mattout, A., Goldberg, M., Tzur, Y., Margalit, A. and Gruenbaum, Y. Specific sequences of lamins are required for interaction with histone H2A tail domains. J. Cell Sci. 120, 77-85.(2007). | View this publication |
| Margalit, A., Neufeld, E., Feinstein, N., Wilson, K.L., Podbilewicz, B. and Gruenbaum, Y. Barrier-to-autointegration factor (BAF) is required for cell fusion timing, vulva formation, germ cell development and survival, DTC migration and adult muscle integrity in C. elegans. J. Cell Biol. 178, 661-73 (2007). | View this publication |
| Margalit, A., Brachner, A., Gotzmann, J, Foisner, F. and Gruenbaum, Y. Barrier to autointegration factor - BAFfling little protein, Trend Cell Biol. 17, 202-208 (2007). | View this publication |
| Melcer, S., Gruenbaum, Y. and Krohne, G. Invertebrate lamins. Exp. Cell. Res. 313, 2157-2166 (2007). | View this publication |
| Penkner, A., Tang, L., Novatchkova, M., Ladurner, M., Fridkin, A., Gruenbaum, Y., Schweizer, D., Loidl, J. and Jantsch, V. The nuclear envelope protein matefin/SUN-1 is required for homologous pairing in C. elegans meiosis. Dev. Cell 12, 873-885 (2007). | View this publication |
| Arturo Briva, Istva´n Vada´sz, Emilia Lecuona, Lynn C. Welch, Jiwang Chen, Laura A. Dada, Humberto E. Trejo, Vidas Dumasius, Zaher S.
Azzam, Pavlos M. Myrianthefs, Daniel Batlle, Yosef Gruenbaum, Jacob I. Sznajder
High CO2 Levels Impair Alveolar Epithelial Function Independently of pH (2007) | View this publication |
| Foeger, N., Wiesel, N., Mcke, N., Lotsch, D., Kreplak, L., Aebi, U., Gruenbaum, Y. and Herrmann, H. Solubility properties and specific assembly pathways of the B-type lamin from Caenorhabditis elegans. J. Struc. Biol. 155, 340-350 (2006).
| View this publication |
| Melcer, S. and Gruenbaum, Y. Nuclear morphology: When round kernels do the Charleston.
Current Biology. 6, R195-197 (2006).
| View this publication |
| Prokocimer, M., Margalit, A. and Gruenbaum Y. The nuclear lamina and its proposed roles in
tumorigenesis: Projection on the hematologic malignancies and future targeted therapy. J. Struc. Biol. 155, 351-360 (2006).
| View this publication |
| Tzur, Y., Wilson, K.L. and Gruenbaum, Y. SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton. Nat. Rev. Mol. Cell Biol. 7, 782-788 (2006) | View this publication |
| Tzur, Y.B., Margalit, A., Melamed-Book, N. and Gruenbaum Y. Matefin/SUN-1 is a nuclear envelope receptor for CED-4 during Caenorhabditis elegans apoptosis. Proc. Nat. Acad. Sci. USA 103, 13397-13402 (2006). | View this publication |
| Gruenbaum, Y., Raska, I. and Herrmann, H. The cell nucleus becoming center stage. EMBO Rep. in press (2006) | View this publication |
| Mattout, A., Goldberg, M., Tzur, Y., Margalit, A. and Gruenbaum, Y. Specific sequences of lamins are required for interaction with histone H2A tail domains. J. Cell Sci. in press. (2006). | View this publication |
| Mattout, A., Dechat, T., Adam, S.A., Goldman, R.D. and Gruenbaum, Y. Nuclear lamins, diseases and aging. Curr. Opi. Cell Biol. 18, 335-341 (2006). | View this publication |
| Haithcock, E., Dayani, Y., Neufeld, E., Zahand, A.J., Feinstein. N., Mattout, A., Gruenbaum,
Y. and Liu, J. Age-related changes of nuclear architecture in C. elegans. Proc. Natl. Acad. Sci. USA. 102, 16690-16695 (2005).
| View this publication |
| Margalit, A., Vlcek, S., Foisner, R. and Gruenbaum Y. The Breaking and making of the
nuclear envelope. J. Cell. Biochem. 95, 454-465 (2005).
| View this publication |
| Margalit, A., Segura-Totten, M., Gruenbaum, Y. and Wilson, K.L. BAF has essential
mutually-dependent roles with lamin B and LEM-domain proteins in chromosome segregation and nuclear lamina assembly in C. elegans. Proc. Natl. Acad. Sci. USA. 102, 3290-3295. (2005).
| View this publication |
| Gruenbaum Y., Margalit, A., Goldman R.D., Shumaker, D. and Wilson K.L. The nuclear
lamina comes of age. Nat. Rev. Cell Mol. Biol. 6, 21-31 (2005).
| View this publication |
| Fridkin, A., Margalit, A. and Gruenbaum, Y. The "elegans" of the nuclear lamina. Zellbiologie
Aktuell., (2005).
| View this publication |
| Margalit, A., Liu, J. Fridkin, A. Wilson, K.L. and Gruenbaum, Y A lamin-dependent pathway that regulates nuclear organization, cell cycle progression and germ cell development. Novartis. Found. Sym. Ed. Goldman, R.D. 231-240 (2005). | View this publication |
| Cohen, M., Wilson, K.L. and Gruenbaum Y. Membrane proteins of the nuclear pore complex. In Nuclear Import and Export in Plants and Animals. Ed. Vitaly Citovsky. Landes Bioscience p28-34 (2005). | View this publication |
| Goldman, R.D., Shumaker, D.K., Erdos, M.R., Eriksson, M., Goldman, A.E., Gordon, L.B.,
Gruenbaum, Y., Khuon, S., Mendez, M., Varga, R. and Collins, F.S. Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford Progeria syndrome. Proc. Natl. Acad. Sci. USA 101, 8963-8968 (2004).
| View this publication |
| Fridkin, A., Mills, E. Margalit, A., Neufeld, E., Lee, K.K., Feinstein, N., Cohen, M., Wilson,
K.L. and Gruenbaum, Y. Matefin, a C. elegans germline-specific SUN-domain nuclear
membrane protein, is essential for early embryonic and germ cell development. Proc. Natl.
Acad. Sci. USA 101, 6987-6992 (2004).
| View this publication |
| Adam, S. and Gruenbaum Y. Exploring the nuclear envelopes properties and roles.
BioAssay 26, 814-826 (2004).
| View this publication |
| Fridkin, A., Karabinos, A. Gruenbaum, Y. Intermediate Filaments in Caenorhabditis elegans.
In Methods in Cell Biology. Intermediate Filament Cytoskeleton. Elsevier. Ed. Omary, B. and
Coulombe, P. 78, 703-718 (2004).
| View this publication |
| Podbilewicz, B, and Gruenbaum, Y. Live imaging in C. elegans. In Cells Cold
Spring Harbor Laboratory Press. Ed. Goldman R.D, and Spector, D. 371-383 (2004).
| View this publication |
| Liu, J., Lee, K.K., Segura-Totten, M., Neufeld, E., Wilson, K.L. and Gruenbaum, Y.
MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division. Proc. Natl. Acad. Sci. USA 100, 4598-4603 (2003).
| View this publication |
| Cohen, M., Feinstein, N, Wilson, K.L. and Gruenbaum, Y. Membrane protein gp210 is
essential for nuclear pore formation, nuclear import and cell viability. Mol. Biol. Cell 14, 4230-4237 (2003).
| View this publication |
| Rotkopf, S., Laronne, A., Hellman, A., Gruenbaum, Y. Porter, A.C. and Brandeis, M.
Synchronization of interphase events depends neither on mitosis nor on cdk1. Mol. Biol. Cell 14, 3730-3740 (2003).
| View this publication |
| Mattout A. and Gruenbaum, Y. The role of the nuclear lamina in chromatin organization and
transcriptional regulation. Cell Mol. Life Sci. 60, 2053-2063 (2003).
| View this publication |
| 73. Liu, J., Lee, K.K., Segura-Totten, M., Neufeld, E., Wilson, K.L. and Gruenbaum, Y. MAN1 and
emerin have overlapping function(s) essential for chromosome segregation and cell division. Proc.
Natl. Acad. Sci. USA 100, 4598-4603 (2003).
| View this publication |
| Gruenbaum, Y., Goldman, R.D., Meyuhas, R., Mills, E., Margalit, A., Fridkin, A., Dayani, Y., Prokocimer, M. and Enosh, A. The Nuclear lamina and its functions in the nucleus. Inter. Rev. Cyt. 226, 1-62. (2003).
| View this publication |
| Cohen, M., Tzur, Y., Neufeld E., Feinstein, N., Delannoy, M.R. Wilson, K. and Gruenbaum Y.
Transmission electron microscope studies of the nuclear envelope in C. elegans embryos. J. Struc.
Biol. 140, 232-241 (2002).
| View this publication |
| Kakhlon, O., Gruenbaum, Y. and Cabantchik, Z.Y. Ferritin expression can modulate cell cycle dynamics and cell responsiveness to H-RAS induced growth via expansion of the labile iron pool.
Biochem J. 363, 431-436 (2002).
| View this publication |
| 69. Kakhlon, O., Gruenbaum, Y. and Cabantchik, Z.Y. Repression of ferritin expression modulates cell responsiveness to H-RAS induced growth. Bioch. Soc. Trans. 30, 777780 (2002). | View this publication |
| Tzur, Y.B. Hersh , B.M., Horvitz, H.R.and Gruenbaum, Y. The fate of the nuclear lamina during
C. elegans apoptosis. J. Struc. Biol. 137, 146153 (2002).
| View this publication |
| Goldman, R.D., Gruenbaum, Y., Moir, R.D., Shumaker, D.K. and Spann, T.P. Nuclear
lamins: building blocks of nuclear architecture. Genes Dev. 16, 533 547 (2002).
| View this publication |
| Tour, E., Pillemer, G., Gruenbaum, Y. and Fainsod, A. Gbx2 interacts with Otx2 and patterns the anterior-posterior axis during gastrulation. Mech. Dev. 112, 141-151 (2002).
| View this publication |
| Gruenbaum. Y., Lee, K.K., Liu, J., Cohen M. and Wilson, K.L. The expression, lamin-
dependent localization and RNAi depletion phenotype for emerin in C. elegans. J. Cell Sci. 115, 923-929 (2002).
| View this publication |
| Lee, K.K., Starr, D. Spann, P., Cohen, M. Han, M., Wilson K.L. and Gruenbaum, Y. Lamin-dependent localization of UNC-84, a protein required for nuclear migration in C. elegans. Mol. Biol. Cell 13, 892-901 (2002). | View this publication |
| Tour, E., Pillemer, G., Gruenbaum, Y. and Fainsod, A. Otx-2 can activate the isthmic
organizer genetic network in the Xenopus embryo. Mech. Dev. 110, 313 (2002).
| View this publication |
| Tour, E., Pillemer, G., Gruenbaum, Y. and Fainsod, A. The two Xenopus Gbx2 genes exhibit
similar, but not identical expression patterns and can affect head formation. FEBS Letters 507, 205-209 (2002).
| View this publication |
| Cohen, M., Wilson, K.L. and Gruenbaum, Y. Membrane proteins of the nuclear pore
complex: Gp210 is conserved in Drosophila, C. elegans and Arabidopsis. In Textbook of
Gene Therapy and Molecular Biology: "From basic mechanism to clinical applications". Ed.
T. Boulikas. Vol. 6, 47-55. (2001).
| View this publication |
| Wilson, K.L., Benavente, R,, Burke, B., Craigie, R., Foisner, R., Furukawa, K., Gerace, L.,
Goldman, R.D, Gruenbaum, Y., Harris, C., Hutchison, C.J., Krohne, G., Morris, G.E., Otto, H., Simon, A.J., Worman, H.J. Problems with LAP nomenclature. Nat Cell Biol 3, E90
(2001).
| View this publication |
| Kakhlon, O., Gruenbaum, Y. and Cabantchik, Z.Y. Repression of the heavy ferritin chain
increases the labile iron pool of human K562 cells. Biochem J. 356, 311-316 (2001).
| View this publication |
| Kakhlon, O., Gruenbaum, Y. and Cabantchik, Z.Y. Repression of ferritin expression increases the labile iron pool, oxidative stress and short term growth of human erythroleukemia cells. Blood 97, 2863-2871(2001).
| View this publication |
| Cohen, M., Lee, K.K., Wilson, K.L. and Gruenbaum Y. Transcriptional repression, apoptosis, human disease and the functional evolution of the nuclear lamina. Trends Bichem. Sci (TiBS), 26, 41-47 (2001).
| View this publication |
| Liu, J., Rolef Ben-Shahar, T., Riemer, D., Treinin, M., Spann, P., Weber, K., Fire, A. and
Gruenbaum, Y. The Caenorhabditis elegans lamin gene is essential and is required for nuclear
organization, mitotic progression, chromosome segregation and spatial organization of nuclear pore
complexes. Mol. Biol. Cell 11, 39373947 (2000).
| View this publication |
| Lee, K.L., Gruenbaum, Y., Spann, P. Liu, J., Wilson, K.L. C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis Mol. Biol. Cell. 11, 3089-3099 (2000).
| View this publication |
| Chen, F., Hersh, B.M., Conradt, B., Zhou, Z., Riemer, D., Gruenbaum, Y. and Horvitz, R.H. CED-4 translocates to nuclear membranes during C. elegans programmed cell death. Science 287, 1485-1489 (2000).
| View this publication |
| Gruenbaum, Y, Wilson, K.L., Harel, A., Goldberg, M. and Merav, C. Nuclear lamins: Peripheral proteins with fundamental functions. J. Struct. Biol. 129, 313323 (2000).
| View this publication |
| Goldberg M., Gruenbaum, Y. and Brandies, M. Use of green fluorescence fusion proteins for efficient and reliable in vitro binding assays. TIGS/TIBS Technical Tips On Line(2000). | View this publication |
| Goldberg, M., Harel, A., and Gruenbaum, Y. The nuclear lamina: Molecular organization and interaction with chromatin. Critical Reviews in Eukaryotic Gene Expression. 9, 285-293 (1999).
| View this publication |
| Goldberg, M., Nili, E., Cojocaru, G., Tzur, Y.B. Berger, R., Brandies, M., Rechavi, G.,
Gruenbaum, Y. and. Simon, A.J. Functional Organization of the Nuclear Lamina. In Textbook of Gene Therapy and Molecular Biology: "From basic mechanism to clinical applications". Ed. T. Boulikas. Vol. 4, 143-158. (1999).
| View this publication |
| Bercovich, D., Regev, Z., Ratz, T, Luder, A, Plotsky, Y and Gruenbaum, Y. The quantitative ratio of primer pairs and the annealing temperature affect PCR products in multi-band amplification. BioTechniques 27, 762-770 (1999).
| View this publication |
| Bercovich, D., Plotsky, Y. and Gruenbaum Y. Improved protocol for using avian red blood cells as substrates for the polymerase chain reaction. BioTechniques. 26, 1080-1082 (1999).
| View this publication |
| Goldberg, M., Harel, A., Rechsteiner, T., Weiss, A.M., Richmond, T. and Gruenbaum, Y.Interactions between the tail domain of lamin Dm0 and histones H2A and H2B. Proc. Natl. Acad. Sci. USA. 96, 2852-2857 (1999).
| View this publication |
| Harel, A., Goldberg, M., Ulitzur, N. and Gruenbaum, Y. Structural organization and biological roles of the nuclear lamina. In Textbook of Gene Therapy and Molecular Biology: "From basic mechanism to clinical applications". Ed. T. Boulikas (1998) vol. 1 pp529-542 | View this publication |
| Goldberg, M., Lu, H., Ashery-Padan, R., Weiss, A.M., Fisher, P.A., Gruenbaum, Y.
and Wolfner, M.F. Interactions between Drosophila nuclear envelope proteins: lamin, otefin and YA. Mol. Cell. Biol. 18, 4315-4323 (1998).
| View this publication |
| Gruenbaum, Y., Landesman, Y., Drees, B., Bare, J.W., Saumweber, H., Paddy, M.R., Sedat, J.W. Smith, D.E., Benton, B.M. and Fisher, P.A. Drosophila nuclear lamin precursor is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene. J. Cell Biol. 106, 585-596 (1988).
| View this publication |
| Julie C. Kiefer
Pushing the Envelope: Developmental Regulation by the Nuclear Lamina | View this publication |