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Daniel Z. Bar, Ester Neufeld, Naomi Feinstein, and Yosef Gruenbaum Gliotoxin Reverses Age-Dependent Nuclear Morphology Phenotypes, Ameliorates Motility, but Fails to Affect Lifespan of Adult Caenorhabditis elegans (2009)View this publication
Miron Prokocimer, Maya Davidovich, Malka Nissim-Rafinia, Naama Wiesel-Motiuk, Daniel Z. Bar, Rachel Barkan, Eran Meshorer, Yosef Gruenbaum Nuclear lamins: key regulators of nuclear structure and activities (2009)View this publication
Kfir Sharabi, Anat Hurwitz, Amos J. Simon, Greg J. Beitel, Richard I. Morimoto, Gideon Rechavi, Jacob I. Sznajder, and Yosef Gruenbaum, Elevated CO2 levels affect development, motility, and fertility and extend life span in Caenorhabditis elegans (2009)View this publication
Yosef Gruenbaum The curious case of The ageing cells (2009)View this publication
Eran Meshorer and Yosef Gruenbaum NURd keeps chromatin young (2009)View this publication
Naama Wiesel, Anna Mattout, Shai Melcer, Naomi Melamed-Book, Harald Herrmann, Ohad Medalia, Ueli Aebi, Yosef Gruenbaum Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins (2008)View this publication
Eran Meshorer and Yosef Gruenbaum Gone with the Wnt/Notch: stem cells laminopathies, progeria, and aging (2008)View this publication
Eran Meshorer & Yosef Gruenbaum Rejuvenating premature aging (2008)View this publication
Cohen M, Santarella R, Wiesel N, Mattaj I, Gruenbaum Y. Electron microscopy of lamin and the nuclear lamina in Caenorhabditis elegans. (2008)View this publication
Mattout, A., Goldberg, M., Tzur, Y., Margalit, A. and Gruenbaum, Y. Specific sequences of lamins are required for interaction with histone H2A tail domains. J. Cell Sci. 120, 77-85.(2007). View this publication
Margalit, A., Neufeld, E., Feinstein, N., Wilson, K.L., Podbilewicz, B. and Gruenbaum, Y. Barrier-to-autointegration factor (BAF) is required for cell fusion timing, vulva formation, germ cell development and survival, DTC migration and adult muscle integrity in C. elegans. J. Cell Biol. 178, 661-73 (2007).View this publication
Margalit, A., Brachner, A., Gotzmann, J, Foisner, F. and Gruenbaum, Y. Barrier to autointegration factor - BAFfling little protein, Trend Cell Biol. 17, 202-208 (2007).View this publication
Melcer, S., Gruenbaum, Y. and Krohne, G. Invertebrate lamins. Exp. Cell. Res. 313, 2157-2166 (2007).View this publication
Penkner, A., Tang, L., Novatchkova, M., Ladurner, M., Fridkin, A., Gruenbaum, Y., Schweizer, D., Loidl, J. and Jantsch, V. The nuclear envelope protein matefin/SUN-1 is required for homologous pairing in C. elegans meiosis. Dev. Cell 12, 873-885 (2007).View this publication
Arturo Briva, Istva´n Vada´sz, Emilia Lecuona, Lynn C. Welch, Jiwang Chen, Laura A. Dada, Humberto E. Trejo, Vidas Dumasius, Zaher S. Azzam, Pavlos M. Myrianthefs, Daniel Batlle, Yosef Gruenbaum, Jacob I. Sznajder High CO2 Levels Impair Alveolar Epithelial Function Independently of pH (2007)View this publication
Foeger, N., Wiesel, N., Mcke, N., Lotsch, D., Kreplak, L., Aebi, U., Gruenbaum, Y. and Herrmann, H. Solubility properties and specific assembly pathways of the B-type lamin from Caenorhabditis elegans. J. Struc. Biol. 155, 340-350 (2006). View this publication
Melcer, S. and Gruenbaum, Y. Nuclear morphology: When round kernels do the Charleston. Current Biology. 6, R195-197 (2006). View this publication
Prokocimer, M., Margalit, A. and Gruenbaum Y. The nuclear lamina and its proposed roles in tumorigenesis: Projection on the hematologic malignancies and future targeted therapy. J. Struc. Biol. 155, 351-360 (2006). View this publication
Tzur, Y., Wilson, K.L. and Gruenbaum, Y. SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton. Nat. Rev. Mol. Cell Biol. 7, 782-788 (2006)View this publication
Tzur, Y.B., Margalit, A., Melamed-Book, N. and Gruenbaum Y. Matefin/SUN-1 is a nuclear envelope receptor for CED-4 during Caenorhabditis elegans apoptosis. Proc. Nat. Acad. Sci. USA 103, 13397-13402 (2006).View this publication
Gruenbaum, Y., Raska, I. and Herrmann, H. The cell nucleus becoming center stage. EMBO Rep. in press (2006)View this publication
Mattout, A., Goldberg, M., Tzur, Y., Margalit, A. and Gruenbaum, Y. Specific sequences of lamins are required for interaction with histone H2A tail domains. J. Cell Sci. in press. (2006).View this publication
Mattout, A., Dechat, T., Adam, S.A., Goldman, R.D. and Gruenbaum, Y. Nuclear lamins, diseases and aging. Curr. Opi. Cell Biol. 18, 335-341 (2006).View this publication
Haithcock, E., Dayani, Y., Neufeld, E., Zahand, A.J., Feinstein. N., Mattout, A., Gruenbaum, Y. and Liu, J. Age-related changes of nuclear architecture in C. elegans. Proc. Natl. Acad. Sci. USA. 102, 16690-16695 (2005). View this publication
Margalit, A., Vlcek, S., Foisner, R. and Gruenbaum Y. The Breaking and making of the nuclear envelope. J. Cell. Biochem. 95, 454-465 (2005). View this publication
Margalit, A., Segura-Totten, M., Gruenbaum, Y. and Wilson, K.L. BAF has essential mutually-dependent roles with lamin B and LEM-domain proteins in chromosome segregation and nuclear lamina assembly in C. elegans. Proc. Natl. Acad. Sci. USA. 102, 3290-3295. (2005). View this publication
Gruenbaum Y., Margalit, A., Goldman R.D., Shumaker, D. and Wilson K.L. The nuclear lamina comes of age. Nat. Rev. Cell Mol. Biol. 6, 21-31 (2005). View this publication
Fridkin, A., Margalit, A. and Gruenbaum, Y. The "elegans" of the nuclear lamina. Zellbiologie Aktuell., (2005). View this publication
Margalit, A., Liu, J. Fridkin, A. Wilson, K.L. and Gruenbaum, Y A lamin-dependent pathway that regulates nuclear organization, cell cycle progression and germ cell development. Novartis. Found. Sym. Ed. Goldman, R.D. 231-240 (2005).View this publication
Cohen, M., Wilson, K.L. and Gruenbaum Y. Membrane proteins of the nuclear pore complex. In Nuclear Import and Export in Plants and Animals. Ed. Vitaly Citovsky. Landes Bioscience p28-34 (2005). View this publication
Goldman, R.D., Shumaker, D.K., Erdos, M.R., Eriksson, M., Goldman, A.E., Gordon, L.B., Gruenbaum, Y., Khuon, S., Mendez, M., Varga, R. and Collins, F.S. Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford Progeria syndrome. Proc. Natl. Acad. Sci. USA 101, 8963-8968 (2004). View this publication
Fridkin, A., Mills, E. Margalit, A., Neufeld, E., Lee, K.K., Feinstein, N., Cohen, M., Wilson, K.L. and Gruenbaum, Y. Matefin, a C. elegans germline-specific SUN-domain nuclear membrane protein, is essential for early embryonic and germ cell development. Proc. Natl. Acad. Sci. USA 101, 6987-6992 (2004). View this publication
Adam, S. and Gruenbaum Y. Exploring the nuclear envelopes properties and roles. BioAssay 26, 814-826 (2004). View this publication
Fridkin, A., Karabinos, A. Gruenbaum, Y. Intermediate Filaments in Caenorhabditis elegans. In Methods in Cell Biology. Intermediate Filament Cytoskeleton. Elsevier. Ed. Omary, B. and Coulombe, P. 78, 703-718 (2004). View this publication
Podbilewicz, B, and Gruenbaum, Y. Live imaging in C. elegans. In Cells Cold Spring Harbor Laboratory Press. Ed. Goldman R.D, and Spector, D. 371-383 (2004). View this publication
Liu, J., Lee, K.K., Segura-Totten, M., Neufeld, E., Wilson, K.L. and Gruenbaum, Y. MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division. Proc. Natl. Acad. Sci. USA 100, 4598-4603 (2003). View this publication
Cohen, M., Feinstein, N, Wilson, K.L. and Gruenbaum, Y. Membrane protein gp210 is essential for nuclear pore formation, nuclear import and cell viability. Mol. Biol. Cell 14, 4230-4237 (2003). View this publication
Rotkopf, S., Laronne, A., Hellman, A., Gruenbaum, Y. Porter, A.C. and Brandeis, M. Synchronization of interphase events depends neither on mitosis nor on cdk1. Mol. Biol. Cell 14, 3730-3740 (2003). View this publication
Mattout A. and Gruenbaum, Y. The role of the nuclear lamina in chromatin organization and transcriptional regulation. Cell Mol. Life Sci. 60, 2053-2063 (2003). View this publication
73. Liu, J., Lee, K.K., Segura-Totten, M., Neufeld, E., Wilson, K.L. and Gruenbaum, Y. MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division. Proc. Natl. Acad. Sci. USA 100, 4598-4603 (2003). View this publication
Gruenbaum, Y., Goldman, R.D., Meyuhas, R., Mills, E., Margalit, A., Fridkin, A., Dayani, Y., Prokocimer, M. and Enosh, A. The Nuclear lamina and its functions in the nucleus. Inter. Rev. Cyt. 226, 1-62. (2003). View this publication
Cohen, M., Tzur, Y., Neufeld E., Feinstein, N., Delannoy, M.R. Wilson, K. and Gruenbaum Y. Transmission electron microscope studies of the nuclear envelope in C. elegans embryos. J. Struc. Biol. 140, 232-241 (2002). View this publication
Kakhlon, O., Gruenbaum, Y. and Cabantchik, Z.Y. Ferritin expression can modulate cell cycle dynamics and cell responsiveness to H-RAS induced growth via expansion of the labile iron pool. Biochem J. 363, 431-436 (2002). View this publication
69. Kakhlon, O., Gruenbaum, Y. and Cabantchik, Z.Y. Repression of ferritin expression modulates cell responsiveness to H-RAS induced growth. Bioch. Soc. Trans. 30, 777780 (2002).View this publication
Tzur, Y.B. Hersh , B.M., Horvitz, H.R.and Gruenbaum, Y. The fate of the nuclear lamina during C. elegans apoptosis. J. Struc. Biol. 137, 146153 (2002). View this publication
Goldman, R.D., Gruenbaum, Y., Moir, R.D., Shumaker, D.K. and Spann, T.P. Nuclear lamins: building blocks of nuclear architecture. Genes Dev. 16, 533 547 (2002). View this publication
Tour, E., Pillemer, G., Gruenbaum, Y. and Fainsod, A. Gbx2 interacts with Otx2 and patterns the anterior-posterior axis during gastrulation. Mech. Dev. 112, 141-151 (2002). View this publication
Gruenbaum. Y., Lee, K.K., Liu, J., Cohen M. and Wilson, K.L. The expression, lamin- dependent localization and RNAi depletion phenotype for emerin in C. elegans. J. Cell Sci. 115, 923-929 (2002). View this publication
Lee, K.K., Starr, D. Spann, P., Cohen, M. Han, M., Wilson K.L. and Gruenbaum, Y. Lamin-dependent localization of UNC-84, a protein required for nuclear migration in C. elegans. Mol. Biol. Cell 13, 892-901 (2002).View this publication
Tour, E., Pillemer, G., Gruenbaum, Y. and Fainsod, A. Otx-2 can activate the isthmic organizer genetic network in the Xenopus embryo. Mech. Dev. 110, 313 (2002). View this publication
Tour, E., Pillemer, G., Gruenbaum, Y. and Fainsod, A. The two Xenopus Gbx2 genes exhibit similar, but not identical expression patterns and can affect head formation. FEBS Letters 507, 205-209 (2002). View this publication
Cohen, M., Wilson, K.L. and Gruenbaum, Y. Membrane proteins of the nuclear pore complex: Gp210 is conserved in Drosophila, C. elegans and Arabidopsis. In Textbook of Gene Therapy and Molecular Biology: "From basic mechanism to clinical applications". Ed. T. Boulikas. Vol. 6, 47-55. (2001). View this publication
Wilson, K.L., Benavente, R,, Burke, B., Craigie, R., Foisner, R., Furukawa, K., Gerace, L., Goldman, R.D, Gruenbaum, Y., Harris, C., Hutchison, C.J., Krohne, G., Morris, G.E., Otto, H., Simon, A.J., Worman, H.J. Problems with LAP nomenclature. Nat Cell Biol 3, E90 (2001). View this publication
Kakhlon, O., Gruenbaum, Y. and Cabantchik, Z.Y. Repression of the heavy ferritin chain increases the labile iron pool of human K562 cells. Biochem J. 356, 311-316 (2001). View this publication
Kakhlon, O., Gruenbaum, Y. and Cabantchik, Z.Y. Repression of ferritin expression increases the labile iron pool, oxidative stress and short term growth of human erythroleukemia cells. Blood 97, 2863-2871(2001). View this publication
Cohen, M., Lee, K.K., Wilson, K.L. and Gruenbaum Y. Transcriptional repression, apoptosis, human disease and the functional evolution of the nuclear lamina. Trends Bichem. Sci (TiBS), 26, 41-47 (2001). View this publication
Liu, J., Rolef Ben-Shahar, T., Riemer, D., Treinin, M., Spann, P., Weber, K., Fire, A. and Gruenbaum, Y. The Caenorhabditis elegans lamin gene is essential and is required for nuclear organization, mitotic progression, chromosome segregation and spatial organization of nuclear pore complexes. Mol. Biol. Cell 11, 39373947 (2000). View this publication
Lee, K.L., Gruenbaum, Y., Spann, P. Liu, J., Wilson, K.L. C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis Mol. Biol. Cell. 11, 3089-3099 (2000). View this publication
Chen, F., Hersh, B.M., Conradt, B., Zhou, Z., Riemer, D., Gruenbaum, Y. and Horvitz, R.H. CED-4 translocates to nuclear membranes during C. elegans programmed cell death. Science 287, 1485-1489 (2000). View this publication
Gruenbaum, Y, Wilson, K.L., Harel, A., Goldberg, M. and Merav, C. Nuclear lamins: Peripheral proteins with fundamental functions. J. Struct. Biol. 129, 313323 (2000). View this publication
Goldberg M., Gruenbaum, Y. and Brandies, M. Use of green fluorescence fusion proteins for efficient and reliable in vitro binding assays. TIGS/TIBS Technical Tips On Line(2000). View this publication
Goldberg, M., Harel, A., and Gruenbaum, Y. The nuclear lamina: Molecular organization and interaction with chromatin. Critical Reviews in Eukaryotic Gene Expression. 9, 285-293 (1999). View this publication
Goldberg, M., Nili, E., Cojocaru, G., Tzur, Y.B. Berger, R., Brandies, M., Rechavi, G., Gruenbaum, Y. and. Simon, A.J. Functional Organization of the Nuclear Lamina. In Textbook of Gene Therapy and Molecular Biology: "From basic mechanism to clinical applications". Ed. T. Boulikas. Vol. 4, 143-158. (1999). View this publication
Bercovich, D., Regev, Z., Ratz, T, Luder, A, Plotsky, Y and Gruenbaum, Y. The quantitative ratio of primer pairs and the annealing temperature affect PCR products in multi-band amplification. BioTechniques 27, 762-770 (1999). View this publication
Bercovich, D., Plotsky, Y. and Gruenbaum Y. Improved protocol for using avian red blood cells as substrates for the polymerase chain reaction. BioTechniques. 26, 1080-1082 (1999). View this publication
Goldberg, M., Harel, A., Rechsteiner, T., Weiss, A.M., Richmond, T. and Gruenbaum, Y.Interactions between the tail domain of lamin Dm0 and histones H2A and H2B. Proc. Natl. Acad. Sci. USA. 96, 2852-2857 (1999). View this publication
Harel, A., Goldberg, M., Ulitzur, N. and Gruenbaum, Y. Structural organization and biological roles of the nuclear lamina. In Textbook of Gene Therapy and Molecular Biology: "From basic mechanism to clinical applications". Ed. T. Boulikas (1998) vol. 1 pp529-542View this publication
Goldberg, M., Lu, H., Ashery-Padan, R., Weiss, A.M., Fisher, P.A., Gruenbaum, Y. and Wolfner, M.F. Interactions between Drosophila nuclear envelope proteins: lamin, otefin and YA. Mol. Cell. Biol. 18, 4315-4323 (1998). View this publication
Gruenbaum, Y., Landesman, Y., Drees, B., Bare, J.W., Saumweber, H., Paddy, M.R., Sedat, J.W. Smith, D.E., Benton, B.M. and Fisher, P.A. Drosophila nuclear lamin precursor is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene. J. Cell Biol. 106, 585-596 (1988). View this publication
Julie C. Kiefer Pushing the Envelope: Developmental Regulation by the Nuclear LaminaView this publication